About Book
The Textbook of Pharmacology-I offers a comprehensive foundation for students and professionals seeking to understand the principles and applications of pharmacology. Beginning with a detailed introduction to pharmacology, it defines the subject, traces its historical evolution, and discusses the various sources and nature of drugs, emphasizing essential drug concepts and administration routes. The book thoroughly explores important pharmacological terms such as agonists, antagonists (both competitive and noncompetitive), spare receptors, addiction, tolerance, dependence, and phenomena like tachyphylaxis, idiosyncrasy, and drug allergies. It delves into pharmacokinetics, covering membrane transport and the ADME (absorption, distribution, metabolism, and excretion) processes, along with enzyme induction, inhibition, and elimination kinetics. The pharmacodynamics section explains drug action mechanisms, receptor theories, signal transduction, and receptor types like GPCRs, ion channels, and enzyme-linked receptors. Important concepts like dose-response relationships, therapeutic index, and drug interactions—both pharmacokinetic and pharmacodynamic—are clearly presented. The textbook addresses adverse drug reactions and their clinical significance, while also guiding readers through the drug discovery and evaluation process, including preclinical testing, clinical trial phases, and pharmacovigilance. The structure and function of the peripheral nervous system, especially the autonomic nervous system (ANS), are described with emphasis on neurotransmitters and neurohumoral transmission. The book provides in-depth coverage of parasympathomimetics, parasympatholytics, sympathomimetics, sympatholytics, neuromuscular blockers, and skeletal muscle relaxants. It also examines local anesthetics, and drugs used in myasthenia gravis and glaucoma. A significant portion is devoted to the central nervous system, explaining key neurotransmitters such as GABA, serotonin, and dopamine, and the pharmacology of general anesthetics, sedatives, hypnotics, antiepileptics, alcohols, and psychopharmacological agents including antipsychotics and antidepressants. There is detailed insight into drugs for Parkinson’s and Alzheimer’s diseases, CNS stimulants, nootropics, and opioid analgesics. Lastly, the book discusses critical social and clinical issues related to drug addiction, abuse, tolerance, and dependence, making it a holistic resource for anyone pursuing pharmacological sciences.
About Author
Dr. Vishal R. Rasve currently working as the Assistant Professor and HOD of Pharmacology at Shri Amolak Jain Vidya Prasarak Mandal's, College of Pharmaceutical Science & Research Center, Kada, Ashti, Beed, Maharashtra, India (MH-414202). With over eight years of teaching and research experience. He has completed his B. Pharm from Dr. RGBIPER, Wardha, followed by an M. Pharm in Pharmacology from VBCP, Amravati, and a Ph.D. in Pharmaceutical sciences. He has published numerous research and review articles in esteemed national and international journals, authored three books, and holds four patents, reflecting his dedication to innovation and academic excellence. He has actively participated in national and international seminars, conferences, FDPs, and workshops. He is a life member of the Association of Pharmacy Professionals (APP) and the Education Research and Development Association (ERDA), emphasizing his commitment to advancing pharmaceutical education and research.
Prof. Dasrao Ashok Patil
Prof. Dasrao Ashok Patil is currently working as an assistant professor at Bharat Shikshan Sanstha’s Tatyaraoji More College of Pharmacy, Umerga, Dist. Dharashiv. He has 12 years of experience in academics and research. He completed his B. Pharm from Shivlingeshwar College of Pharmacy, Hasegaon, Latur, Maharashtra, and holds a master’s degree in pharmacology from the School of Pharmacy, S.R.T.M.U., Nanded. Currently, he is pursuing a Ph.D. in pharmaceutical sciences from IPSR, Sardar Patel University, Balaghat, Madhya Pradesh, India. He has actively participated in various national and international seminars and conferences, presenting his research in oral and poster competitions. He has also contributed significantly to the field, having published 22 research and review articles in reputed national and international journals.
Ms. Charushila Pradip Bhintade
Ms. Charushila Pradip Bhintade currently working as Assistant professor at Dattakala College of pharmacy swami chincholi Bhigwan Daund Dist- Pune. She has completed her B. pharm from SVPM College of Pharmacy Malegoan. She holds a Master of Pharmacy degree in Pharmacology from LSDP College of Pharmacy, Pune. She has 1 years of Experience in Academics and research. Also attended various National and International Seminar/Conferences and also presented research work in oral and poster competition. She has published 4 research and 11 review articles in various National and International journals of repute.
Ms. Ashlesha Shankar Gaikwad
Ms. Ashlesha Shankar Gaikwad currently working as Assistant professor at S B Patil College of Pharmacy, Indapur Dist- Pune.. She has completed her B. pharm from SPM’s College of Pharmacy, Akluj. She holds a Master of Pharmacy degree in Pharmacology from LSDP College of Pharmacy, Pune. She has 1 years of Experience in Academics and research. Also attended various National and International Seminar/Conferences and also presented research work in oral and poster competition. She has published 4 research and 11 review articles in various National and International journals of repute.
Mr. Nilesh Sopan Kothare
Mr. Nilesh Sopan Kothare currently working as Assistant Professor at Dhanaji Shelke College of Pharmacy, wakhri Tal daund. Dist. Pune. He has completed her B. pharm from Parikarma College of Pharmacy, kashti, Ahmednagar. He holds a Master of Pharmacy degree in Pharmacology from LSDP College of Pharmacy, Pune. He has 1 years of Experience in Academics and research. Also attended various National and International Seminar/Conferences and also presented research work in oral and poster competition. He has published research and review articles in various National and International journals of repute and also patent.
