About Book
The Textbook of Pharmacology-I offers a comprehensive foundation for students and professionals seeking to understand the principles and applications of pharmacology. Beginning with a detailed introduction to pharmacology, it defines the subject, traces its historical evolution, and discusses the various sources and nature of drugs, emphasizing essential drug concepts and administration routes. The book thoroughly explores important pharmacological terms such as agonists, antagonists (both competitive and noncompetitive), spare receptors, addiction, tolerance, dependence, and phenomena like tachyphylaxis, idiosyncrasy, and drug allergies. It delves into pharmacokinetics, covering membrane transport and the ADME (absorption, distribution, metabolism, and excretion) processes, along with enzyme induction, inhibition, and elimination kinetics. The pharmacodynamics section explains drug action mechanisms, receptor theories, signal transduction, and receptor types like GPCRs, ion channels, and enzyme-linked receptors. Important concepts like dose-response relationships, therapeutic index, and drug interactions—both pharmacokinetic and pharmacodynamic—are clearly presented. The textbook addresses adverse drug reactions and their clinical significance, while also guiding readers through the drug discovery and evaluation process, including preclinical testing, clinical trial phases, and pharmacovigilance. The structure and function of the peripheral nervous system, especially the autonomic nervous system (ANS), are described with emphasis on neurotransmitters and neurohumoral transmission. The book provides in-depth coverage of parasympathomimetics, parasympatholytics, sympathomimetics, sympatholytics, neuromuscular blockers, and skeletal muscle relaxants. It also examines local anesthetics, and drugs used in myasthenia gravis and glaucoma. A significant portion is devoted to the central nervous system, explaining key neurotransmitters such as GABA, serotonin, and dopamine, and the pharmacology of general anesthetics, sedatives, hypnotics, antiepileptics, alcohols, and psychopharmacological agents including antipsychotics and antidepressants. There is detailed insight into drugs for Parkinson’s and Alzheimer’s diseases, CNS stimulants, nootropics, and opioid analgesics. Lastly, the book discusses critical social and clinical issues related to drug addiction, abuse, tolerance, and dependence, making it a holistic resource for anyone pursuing pharmacological sciences.
About Author
Ms. Neha Goel is a distinguished academician and currently serves as Associate Professor at the Rajiv Gandhi Institute of Pharmacy, Constituent Unit of AKS University, Satna, (M.P.). With an illustrious career spanning several years, Ms. Goel has made significant contributions to the field of pharmacy education and research. She holds a Master in Pharmacy and is widely respected for her in the field. Ms. Goel’s academic journey is marked by numerous achievements, she has played a pivotal role in shaping the careers of aspiring pharmacists. Ms. Goel has been instrumental in implementing innovative teaching methodologies and fostering an environment conducive to research and learning. She has bagged 1st class academic degree Master of Pharmacy (Pharmacology) from RGPV, Bhopal, (M.P.). She has published various review and research papers in national and international journals. She is author of 4 books and writes various book chapters of 18 different books. She is actively participating in academic & research work & also involved in various extracurricular activities. She has participated in various national & international conferences & giving paper & poster presentation & received best poster award & received Research Excellence Award in “Herbal Drugs”. She is life member of APTI (Association of Pharmaceutical Teachers of India) and SPER (Society of Pharmaceutical Education & Research). With over 10 years of experience in teaching, she has established herself as a respected figure in the field of pharmaceutical education. Her commitment to fostering a holistic learning environmental underscores her dedication to the development of her students.
Dr. Md Nurtaj Ali is an Assistant Professor in the Department of Pharmacology at Uttaran Institute of Medical Sciences and a clinical pharmacy specialist. With a Pharm D (PB) from JNTUH and clinical experience at KIMS Hospital, his expertise spans nephrology research, diabetic pharmacotherapy, and medication safety. A dedicated researcher, he has conducted pivotal studies on CKD-related anemia and the efficacy of modern therapeutics. His writing blends academic rigor with practical clinical insights, aiming to advance pharmaceutical education and patient care standards.
Dr. Smriti Tiwari is a Pharm.D professional and Lecturer at Teerthanker Mahaveer College of Pharmacy, Teerthanker Mahaveer University, Moradabad, Uttar Pradesh. She has published numerous research papers in Scopus-indexed journals and is actively engaged in teaching, clinical training, and research. She is actively involved in teaching undergraduate and postgraduate students and contributes to academic and research activities in the field of pharmaceutical sciences. Her academic interests include pharmacology, drug mechanisms, therapeutic evaluation, adverse drug reactions, and patient-centered pharmaceutical care. She is also involved in guiding students in research work, academic projects, and case-based learning, reflecting her commitment to quality education and practical understanding.
Dr. Krishnendu Ray is a distinguished academician and administrator in the field of pharmaceutical education, currently serving as the Principal of Uttaran Institute of Medical Sciences, Khana Junction, Purba Burdwan, West Bengal. With nearly two decades of dedicated service, he has made significant contributions to teaching, research, and institutional development. He has been leading the institution effectively for the past 20 months, fostering academic excellence and professional growth. Prior to this role, he gained 17 years of valuable experience at a reputed pharmacy college, strengthening his expertise in pharmaceutical sciences. Dr. Ray is known for his commitment to quality education, student mentorship, and curriculum development. His leadership continues to inspire innovation and progress in pharmacy education.
Prof. (Dr.) Manoj Kumar Katual (M.Pharm, MBA, PhD) is a distinguished academician currently serving as Professor and Principal at Florence College of Pharmacy. With over 18 years of teaching and research experience, he has held key leadership roles as Dean and Head of Institutions in various universities and colleges across India. He is the Editor-in-Chief of the reputed African Journal of Health Sciences and has extensive expertise in pharmaceutical, biomedical, and healthcare research, particularly in formulation and development advancements. Dr. Katual has published over 125 scientific papers with more than 9300 citations, an H-index of 42, and an i-10 index of 210, and was recognized among India’s Top 2% Scientists in Pharmaceutical Sciences (2024). He has authored and edited more than 30 books, contributed as a series and guest editor, and holds 6 patents, including 5 granted. A recipient of Research Excellence Awards (2020–2024) and over 35 national and international honors, he continues to contribute significantly to pharmaceutical education and research
