About Book
Textbook of Pharmaceutical Organic Chemistry–III is a comprehensive academic resource designed to provide in-depth knowledge of advanced concepts in organic chemistry with a strong pharmaceutical orientation. The book begins with a detailed exploration of stereoisomerism, particularly optical isomerism, explaining fundamental concepts such as optical activity, enantiomerism, diastereoisomers, and meso compounds. It highlights the importance of symmetry elements and introduces both DL and RS systems of nomenclature for chiral molecules. The text further discusses racemic mixtures, their modification, and methods of resolution, along with principles of asymmetric synthesis. Geometrical isomerism is thoroughly covered with nomenclature systems like cis-trans and E-Z, along with methods for determining configurations. The book also elaborates on conformational isomerism in ethane, n-butane, and cyclohexane, providing a clear understanding of molecular stability and structure. Advanced topics such as atropisomerism, stereospecific, and stereoselective reactions are also included to enhance conceptual clarity. A significant portion of the book is devoted to heterocyclic compounds, starting with pyrrole, furan, and thiophene, covering their synthesis, reactivity, and medicinal applications. It further extends to important heterocycles like pyrazole, imidazole, oxazole, thiazole, pyridine, quinoline, acridine, and indole, emphasizing their pharmaceutical importance. The book also explains the basicity of pyridine and includes detailed discussions on biologically significant compounds such as pyrimidines, purines, and azepines. Additionally, it covers a wide range of organic reactions of synthetic importance, including various reduction, oxidation, and rearrangement reactions. Key reactions such as Clemmensen, Birch, Wolff–Kishner reduction, Oppenauer oxidation, Beckmann rearrangement, and Claisen–Schmidt condensation are explained with relevance to pharmaceutical synthesis. Overall, this textbook serves as an essential guide for pharmacy students, helping them build a strong foundation in organic chemistry concepts and their applications in drug development and medicinal chemistry.
About Author
Dr. Raka Kalpesh Chandrakant is a dedicated academician serving as an Assistant Professor at S.V.N.H.T’S College of B. Pharmacy, Rahuri Factory, Maharashtra. He has over 15 years of teaching experience with strong expertise in pharmaceutical sciences and research methodology. He holds a Ph.D. in Pharmacy from Oriental University, Indore, along with an M. Pharm in Pharmaceutical Chemistry from Dr. D. Y. Patil Institute, Pune. His academic journey began with a B. Pharm from Pravara Rural College of Pharmacy, affiliated with Savitribai Phule Pune University. Dr. Raka has published 15 research papers in reputed Scopus and UGC Care-listed journals, reflecting his active research contributions. He also holds two patents (one Indian and one international) and has completed multiple AICTE and ATAL-sponsored Faculty Development Programmes.
Dr. Surwase Kumar Pralhadrao is a distinguished academician currently serving as Principal at Kishori College of Pharmacy Beed, with over 18 years of teaching and administrative experience. He completed his Ph.D. in Pharmaceutical Chemistry in 2024 from Oriental University, Indore, strengthening his expertise in the field. His academic qualifications also include M. Pharm and B. Pharm from reputed institutions. Dr. Surwase has extensive experience in academic leadership, regulatory inspections, and laboratory administration. He has contributed significantly to research through multiple publications and patents in pharmaceutical sciences. He actively participates in conferences, FDPs, and industry training programs, reflecting his commitment to continuous professional growth.
Dr. R. Betsy Clarebel is an Assistant Professor in the Department of Chemistry at Jayaraj Annapackiam College for Women (Autonomous), Periyakulam. She completed her Ph.D. in Chemistry from St. Joseph’s College, Tiruchirappalli, with research focused on biomimetic oxidation of bioactive molecules. Her research interests include biomimetic chemistry, oxidation kinetics, and nanomaterials. She has published several research articles in reputed International and National journals and has presented papers at various conferences. She is also a recipient of multiple academic awards, including Best Research Scholar.
Mr. Ashok A. Chopane is presently working as an Assistant Professor, SCSSS’s, Sitabai Thite College of Pharmacy, Shirur. He has three years of Teaching and Innovative Research experience. He has completed his B.Pharm Anand Charitable Santha’s College of Pharmaceutical Science & Research, Ashti [Affiliated with Dr. Babasaheb Ambedkar Marathwada University Aurangabad]. and M. Pharm Completed in Department of Pharmaceutical Chemistry from Dr. Vithalrao Vikhe Patil Foundation's College of pharmacy, Vilad Ghat, Ahmednagar [Affiliated with Savitribai Phule Pune University, Pune]. He has Published Patents, Books & Several Research and Review Papers in International Journals of repute and also attends various International and National seminars/Conferences/FDPs/Workshops and Webinars.
Dr. M. I. Ahymah Joshy is Assistant Professor in Chemistry at Jayaraj Annapackiam College for Women (Autonomous), Periyakulam, Theni, with 6 months of teaching experience. She published papers in 13 International journals and 2 Indian journals. She received NDF by AICTE India. She is a life member of the Society for Biomaterials and Artificial Organs. Her research interest is Biomaterials and Nanotechnology. She has completed a course in SWAYAM-NPTEL in Applications of Spectroscopic Methods in Molecular Structure Determination. She is actively involved in academic roles such as UBA, Environmental studies committee and Eco club waste water management and green campus.
