About Book
The Text Book of Modern Pharmaceutical Analytical Techniques is a comprehensive guide that introduces students and professionals to the fundamental and advanced concepts of modern analysis used in pharmaceutical sciences. It begins with UV-Visible spectroscopy, explaining its theory, laws, instrumentation, solvent effects, and its wide applications in drug analysis. The next section is IR spectroscopy, covering the theory, molecular vibrations, sample handling, instrumentation of both dispersive and FT-IR spectrometers, factors influencing vibrational frequencies, and practical applications. Spectrofluorimetry is discussed in detail with its theory, factors affecting fluorescence, quenchers, instrumentation, and applications in sensitive pharmaceutical detection. The book also explores Flame Emission Spectroscopy and Atomic Absorption Spectroscopy, focusing on their principles, instrumentation, interferences, and applications in elemental analysis. A substantial section is dedicated to NMR spectroscopy, explaining quantum numbers, principles, instrumentation, solvent use, relaxation processes, signals, chemical shifts, spin-spin coupling, coupling constants, double resonance, FT-NMR, 13C NMR, and its diverse applications in structural elucidation. The chapter on Mass Spectroscopy covers its principle, theory, instrumentation, various ionization techniques such as EI, CI, FAB, MALDI, APCI, ESI, and APPI, along with analyzers like quadrupole and TOF, fragmentation rules, metastable ions, isotopic peaks, and pharmaceutical applications.
The text further elaborates on Chromatography, beginning with an introduction and classification of techniques, followed by detailed discussions on paper, thin layer, ion exchange, column, gas, HPLC, and affinity chromatography—covering principles, apparatus, instrumentation, parameters, resolution factors, and pharmaceutical applications. Electrophoresis is thoroughly explained with different types such as paper, gel, capillary, zone, moving boundary, and isoelectric focusing, highlighting principles, instrumentation, working conditions, factors affecting separation, and practical applications. Another crucial part of the book is X-ray Crystallography, where readers learn about X-ray production, diffraction methods, Bragg’s law, rotating crystal and powder techniques, crystal types, and analytical applications. Finally, the book ends with Immunological Assays, explaining the principles, instrumentation, working conditions, factors affecting separation, and applications of advanced bioanalytical techniques such as RIA, ELISA, and bioluminescence assays.
About Author
Mrs. A. H. Patil is an Assistant Professor at Raigad College of Pharmacy, Mahad, with a specialization in Pharmaceutics. She has been actively engaged in academics for the past 14 years, contributing significantly to teaching and research. Over the years, she has published several review and research papers in reputed national and international journals. Her scholarly work reflects a strong commitment to advancing pharmaceutical sciences and guiding future professionals. Currently, she is pursuing her Ph.D. from Dr. Babasaheb Ambedkar Technological University, Lonere. With her academic expertise and research orientation, she continues to play an important role in the field of pharmacy education and research.
Mr Shekhar Dhalpe has completed M.pharm in Quality Assurance Techniques and Currently pursuing Ph.D in Dr Babasaheb Ambedkar Technological University,Lonere, Raigad.He Has published 2 research paper in national journal and he has 1 Patent. He has a strong interest in pharmaceutical analysis and regulatory sciences. With this book, He aims to simplify analytical concepts for students and professionals in pharmacy.
Ms. Pratiksha S. Pandere is an Assistant Professor in the Department of M. Pharmacy at Dr. Babasaheb Ambedkar Technological University, Lonere. She has been actively engaged in academics for the past 3 years, with a specialization in Pharmaceutical Chemistry. During her career, she has successfully guided B. Pharmacy students in their project work, nurturing their research and analytical skills. She has also contributed to scientific literature by publishing 2 review articles in national journals and 4 research articles in international journals. Her academic and research contributions highlight her dedication to advancing pharmaceutical education and research. With her growing expertise, she continues to inspire students and contribute to the field of Pharmaceutical Chemistry.
Mr. Gajanan Chavan is a seasoned professional holding a Master’s degree in Chemistry with 13 years of rich experience in analytical development within the pharmaceutical industry. He possesses a strong background in generic formulations, technology transfer, and quality compliance for highly regulated markets. Throughout his career, he has contributed to ensuring excellence in pharmaceutical processes and adherence to international standards. His expertise spans both technical and managerial aspects, making him a valuable leader in the industry. Currently, he serves as the Managing Director at GJC Pharmaceutical Pvt. Ltd., where he continues to drive innovation and quality in pharmaceutical practices. His professional journey reflects dedication, leadership, and a commitment to advancing the pharmaceutical sector.
Mr. Manoj Kumar Rathore is a dedicated research scholar in the School of Health and Allied Sciences at Career Point University, Kota, Rajasthan. With over 20 years of expertise in bioanalytical research and development, he has specialized in LC-MS/MS method development and validation. He is currently serving as Section Head of Bioanalytical R&D, where he has successfully developed and validated more than 60 bioanalytical methods for diverse drug molecules. His proficiency includes working with LC-MS/MS platforms across multiple biological matrices such as plasma, serum, urine, and tissues. An accomplished leader, he has guided scientific teams, ensured regulatory compliance, and delivered high-quality results in challenging environments. His strong academic background, including M. Pharm from SGSITS Indore and B. Pharm from LM College Jodhpur, further complements his professional excellence.