About Book
Medicinal Chemistry II is an advanced subject that builds upon the basic principles introduced in Medicinal Chemistry I .It focuses on the detailed study of drugs used in the treatment of various diseases .The subject emphasizes the relationship between chemical structure and biological activity of drugs. Medicinal Chemistry II explains the mechanisms of drug action at molecular and cellular levels. It covers the synthesis, classification, and therapeutic uses of important classes of drugs. Special attention is given to structure–activity relationships (SAR)to understand how structural modifications affect drug potency and selectivity. The book also discusses drug metabolism and biotransformation processes. Concepts of pharmacokinetics such as absorption, distribution, metabolism, and excretion are highlighted. The role of enzymes and receptors in drug action is clearly explained. Medicinal Chemistry II introduces lead compounds and their optimization in drug design. It also covers prodrugs and their importance in improving bioavailability. Case studies of clinically important drugs help bridge theory and practice. The subject provides insight into adverse drug reactions and drug safety. Emphasis is placed on rational drug design for better therapeutic outcomes. The book integrates chemistry with pharmacology and biochemistry. It helps students develop analytical and problem-solving skills. Medicinal Chemistry II prepares students for pharmaceutical research and development. The knowledge gained is useful in clinical pharmacy and industrial applications. The subject strengthens the foundation for advanced studies in pharmaceutical sciences. Overall, Medicinal Chemistry II plays a crucial role in understanding and developing effective and safer medicines.
About Author
Dr.D.Bharathi is currently serving as Professor and Head in the Department of Pharmaceutical Chemistry, Faculty of Pharmacy, SBMCH Campus, Bharath Institute of Higher Education and Research (Deemed University), Chromepet,Chennai44,TamilNadu.She has 14years of dedicated teaching experience and is an established expertise in delivering core subjects of Pharmaceutical Chemistry, including Organic Chemistry, Medicinal Chemistry, and Modern Pharmaceutical Analytical Techniques. She has successfullymentoredandguidednumerousacademicandresearchprojects.
Her research interests are centered on Insilico studies, synthesis, and characterization of substituted heterocyclic derivatives.She also made significant scholarly contributions with 4patents, 3bookchapters, and over 20 publications in peer-reviewed journals. In recognition of her academic excellence, she is a proud recipient of the Best Excellence in Teaching Award.
Dr.M.VijeyAanandhi with over 25years of teaching and research experience, holds B. Pharm, M. Pharm (Pharmaceutical Chemistry), and Ph.D. from The Tamil Nadu Dr.M.G.R. Medical University, Chennai, TN, INDIA. Her academic leadership encompasses senior roles, from Professor & Head to Principal. She has 1,188 citations, h-index 17, i10-index33, and 153 Scopus-indexed publications. She has guided 18 Ph.D. scholars, published 3 books, holds 3patents and earned 16 licenses & certifications and 13courses & certifications. She is a member of professional organizations, recipient of 18 honors & awards contributing significantly to pharmaceutical sciences through teaching, leadership and research.
Dr. Devi Thamizhanban holds a Doctorate in Pharmacy and with over 16years of research experience in the field of Pharmaceutical Analysis. She is currently serving as a Professor in the Department of Pharmaceutical Chemistry &Analysis at Chettinad School of Pharmaceutical Sciences, Chettinad Academy of Research and Education (CARE), TamilNadu, India. Her research experience includes both industrial research in analytical method developments and institutional research. She has authored more than 40 research publications in leading international journals and serves as a recognized reviewer for several reputed journals. She also holds4patents and 2bookchapters.She is a life member of the Association of Pharmaceutical Teachers of India (APTI), Indian Pharmaceutical Graduate Association (IPGA), and the Pharmacy Council of India (PCI).
Dr. Mubarakunnisa.Md is currently working as Associate Professor at Department of Pharmaceutical Chemistry and Analysis, Faculty of Pharmacy, SBMCH, Tamilnadu. She is having 13 years of teaching and Research experience. She is expert in teaching various subjects of Pharmaceutical Chemistry like Inorganic Chemistry, Medicinal Chemistry- 1and 2, Instrumental methods of Analysis, Pharmaceutical Analysis at B. Pharm and Pharm D level. She has guided various projects. Her research interest focuses on LC-MS Method development for estimation of Nitrosamine impurities, in GLIFLOZINS, Biogenic synthesis and characterization of metal nanoparticle using Algae. She has 02 patents and 03 book chapters for her credits. She has published more than 10 research papers in peer scientific journals.
Dr.D. Gnanasekaran is Currently working as Principal at Jaya College of Paramedical Sciences,College of Pharmacy, Thiruninravur, Chennai. He is
B. Pharm from Dr.MGR Medical University, M. Pharm and Ph. D from Vels Institute of Science and Technology (Deemed University), Pallavaram, Chennai ,TamilNadu. He has 15years of experience in teaching and research, has both international and national publication to his credits. He has patents, books and book chapters too. He has received best teacher award for his teaching excellence
Mrs.Saranya.C is an Assistant Professor at the School of Pharmacy, Sri Balaji Vidyapeeth (Deemed to be University).She completed her B.Pharmacy and M. Pharmacy (Pharmaceutical Quality Assurance) at Sri Ramachandra Institute of Higher Education & Research, Chennai, securing top academic honors. She has gained industry exposure through a project internship at Soft Gel Healthcare Pvt. Ltd., specializing in quality assurance and regulatory documentation. A Registered Pharmacist, she has published research in pharmaceutical quality evaluation, with research interests in Pharmaceutical quality systems and regulatory compliance.
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