About Book
The Textbook of Biochemistry provides a comprehensive understanding of the molecular basis of life, systematically covering the fundamental biomolecules and their roles in maintaining biological functions. Beginning with biomolecules, the book introduces carbohydrates, lipids, nucleic acids, amino acids, and proteins, highlighting their classification, chemical nature, and biological significance. The section on bioenergetics explores the concepts of free energy, enthalpy, and entropy, distinguishing between endergonic and exergonic reactions, and explaining redox potential, energy-rich compounds, and the significance of ATP and cyclic AMP. Carbohydrate metabolism is detailed with pathways such as glycolysis, the citric acid cycle, HMP shunt, gluconeogenesis, and glycogen metabolism, along with clinical conditions like G6PD deficiency, glycogen storage diseases, and diabetes mellitus. The discussion on biological oxidation emphasizes the electron transport chain, oxidative phosphorylation, substrate-level phosphorylation, and the effects of inhibitors and uncouplers. Lipid metabolism is explained through the β-oxidation of fatty acids, ketone body metabolism, de novo fatty acid synthesis, and the biological significance of cholesterol, including its conversion into bile acids, steroid hormones, and vitamin D, with attention to disorders such as hypercholesterolemia, atherosclerosis, fatty liver, and obesity. Amino acid metabolism covers transamination, deamination, decarboxylation, the urea cycle and its disorders, catabolism of phenylalanine and tyrosine, and their related diseases such as phenylketonuria, albinism, alkaptonuria, and tyrosinemia. It also highlights the synthesis and significance of key biological molecules such as dopamine, serotonin (5-HT), melatonin, noradrenaline, and adrenaline, alongside heme catabolism, hyperbilirubinemia, and jaundice. The section on nucleic acid metabolism and genetic information transfer describes the biosynthesis and catabolism of purine and pyrimidine nucleotides, clinical conditions like gout, the structural organization of DNA and RNA, DNA replication, transcription, the genetic code, translation, and inhibitors of protein synthesis. The chapter on enzymes introduces their properties, nomenclature, and IUB classification, followed by enzyme kinetics explained through Michaelis and Lineweaver–Burke plots. It also addresses enzyme inhibition with examples, regulatory mechanisms including induction, repression, and allosteric regulation, and their therapeutic and diagnostic applications. Isoenzymes are discussed in medical contexts, while the section on coenzymes explains their structures and biochemical functions. Altogether, this textbook integrates biochemical principles with clinical correlations, making it an essential guide for pharmacy, medical, and life science students, bridging molecular understanding with disease mechanisms and therapeutic applications.
About Author
Prof. (Dr.) Bhoomika is an esteemed academician and researcher, currently serving as a Professor at Department of Life Sciences, School of Biosciences & Technology (SBT), Galgotias University, Greater Noida (U.P.). With a strong foundation in education and a passion for research, she has carved a niche for herself in the field of Biosciences. She holds a doctoral degree from the renowned university, Banaras Hindu University (BHU), Varanasi, where she completed her PhD in 2013. Prior to this, she has received the degree of M.Sc. (Biochemistry) in 2005 and BSc (Zoology, Botany, Chemistry) in 2003 from Dr. Bhimrao Ambedkar University, Agra. Her commitment to academic excellence was further demonstrated through the qualification of National Eligibility Test (CSIR-UGC-NET) in June 2005 and Graduate Aptitude Test in Engineering (GATE) in 2005 and 2006. In addition to her academic achievements, Prof. Bhoomika is a recipient of prestigious accolades, including being awarded the National Post Doctoral Fellowship (N-PDF) from DST-SERB, Junior Research Fellowship (JRF) as well as Senior Research Fellowship (SRF) from DST and Research Fellowship from UGC. Her doctoral and post-doctoral research is majorly focused in the area of crop physiology and biochemistry. She has published her research work extensively in highly reputable journals and national/international conferences. Her research account is also feathered with several patents. She has an extensive experience of working at the laboratories of various premier institutes like National Institute of Plant Genome Research (NIPGR), New Delhi, Indian Agricultural Research Institute (IARI), commonly known as the Pusa Institute, New Delhi, Jawaharlal Nehru University, New Delhi, Banaras Hindu University, Varanasi, Defence Institute of Physiology and Allied Sciences (DIPAS), DRDO, Delhi for around 19 years. Her work has made significant contributions to the field, and she continues to inspire students and peers alike through her passion for teaching and research. Besides scholarly contributions in research, she is a distinguished teaching professional from around 12 years and has a vast experience of teaching a wide range of courses to BSc, MSc and PhD students viz. Biochemistry, Biomolecules, Cell Biology, Molecular Biology, Cytogenetics and Plant Breeding, Genetics, Genetic Disorders, Biology for Engineers, Environmental Science, Bioinstrumentation and Biotechniques, Bioinformatics and other allied courses. With her vast research and teaching experience, she has several edited and text books in her account. Her zeal of learning and polishing skills is prominent through her active participation in various training programs/refresher courses/short term certificate courses, time to time. With her wealth of knowledge, experience, and dedication to advancing the frontiers of knowledge, Prof. (DR.) Bhoomika remains a prominent figure in academia and research, shaping the future of students through her teaching, research, training programs and mentorship.
Dr. Sunita S. Pachori, Associate Professor and Head of the Department of Engineering Sciences and Humanities at Thakur College of Engineering and Technology, Mumbai, is a seasoned academician with over 34.6 years of teaching and research experience. Holding a Ph.D. in Chemistry and an MBA, she has taught various chemistry subjects, guided student projects, presented 23 papers, and published in UGC and Scopus-listed journals. A life member of ISTE and recognized by the University of Mumbai, she has also edited conference proceedings, completed a funded research project, and contributed to curriculum design, ISO audits, and NSS activities. Passionate about social causes, she actively supports health, education, and environmental initiatives, earning several awards for her academic and community contributions.
Abhilasha Gupta is Currently Working as Lecturer (Chemistry) Lzebra College And Institute, Kota, Rajasthan Ph.D Is Running (Chemistry) From Career Point University Kota, Rajasthan. She Has Received Degree Of M.Sc (Chemistry) From Govt. College Bundi, Rajasthan. She Has Published 4 Research Paper and Articles In reputed Journals On Chemistry. Besides Participation in National and International Seminars, Symposium, Conferences and Work Shop. She Is Also Member Of Agriculture Forum For Technical Education Of Farming Society (AFTEFS)
Kuldeep Saini is an Associate Professor at S.D. College of Pharmacy and Vocational Studies, Muzaffarnagar, Uttar Pradesh. He holds an M.Pharm degree and has more than eight years of experience in the pharmacy profession. He has published a number of research and review papers in reputed national and international journals and has actively participated in various national and international conferences and seminars. Over the course of his academic career, he has guided about six M.Pharm students in their research work. With his consistent dedication to teaching and research, he continues to make valuable contributions to the advancement of pharmaceutical education and professional practice.
Mr. Shashank Chaurasiya is currently serving as associate professor in the pharmaceutics department at Daksh Institute of Pharmaceutical Science, Chhatarpur (Madhya Pradesh). He holds M Pharma in pharmaceutics from Ravi Shankar College of Pharmacy, Bhopal (RGPV) he has working also as research scholar. He has 10 years experience in teaching, research and academics. He holds the National and international patent and his contributions 12 publications and some books also on going to publish. He holds an excellence teaching award from SRIJAN Bhopal. He holds Excellence teacher awards from Bansal College of Pharmacy, Bhopal. His interest in research in Noble Drug Delivery System and control release formulation like micro balloons, liposome, microsphere and Expert of GRDDs formulations.He is currently working on Cancer treatment in Noble form. He is a part of many more conferences and seminar
