About Book
Text Book of Advanced Biopharmaceutics & Pharmacokinetics is a comprehensive and concept-driven resource designed to provide in-depth understanding of drug absorption, distribution, and disposition. The book begins with a detailed discussion on drug absorption from the gastrointestinal tract, explaining anatomical features, mechanisms of absorption, and factors influencing drug uptake. It clearly presents the pH-partition theory along with formulation and physicochemical factors such as dissolution rate, dissolution process, and the Noyes–Whitney equation. The role of different dosage forms including solutions, suspensions, capsules, and tablets in gastrointestinal absorption is thoroughly explained. Advanced transport models highlighting permeability, solubility, charge state, pH microclimate, and tight junctions of the GIT are also discussed. The text further elaborates biopharmaceutic considerations in drug product design with emphasis on bioavailability, rate-limiting steps, and drug product performance. In-vitro dissolution testing methods, compendial and alternative approaches, dissolution profile comparisons, and in vitro–in vivo correlation are presented systematically. Pharmacokinetics is covered in detail with basic principles, compartmental and non-compartmental models, and nonlinear kinetics including Michaelis–Menten concepts. Drug interactions involving protein binding, tissue binding, cytochrome P450 enzymes, and transporters are clearly described. A dedicated section on in vivo drug product performance explains bioavailability and bioequivalence studies, study designs, evaluation methods, and regulatory considerations. Permeability studies using in-vitro, in-situ, and in-vivo methods are discussed along with biosimilars and generic substitution. The book also explores the application of pharmacokinetics in modified-release products, targeted drug delivery systems, and biotechnological products. It introduces pharmacokinetics and pharmacodynamics of proteins, peptides, monoclonal antibodies, oligonucleotides, vaccines, and gene therapies. Overall, the book serves as an essential reference for postgraduate students, researchers, and professionals seeking a thorough understanding of advanced biopharmaceutics and pharmacokinetics.
About Author
Dr. Mayank Bansal is a distinguished academician currently working as Professor and Principal at Jaipur College of Pharmacy, Jaipur. He possesses an extensive academic background with qualifications including B. Pharm., M. Pharm. (Pharmaceutics), Ph.D. in Pharmaceutical Sciences, MBA (HRM), MIPL, LLB, PGDPRA, and PGDSM, reflecting his multidisciplinary expertise. With over 20 years of teaching experience, he has made significant contributions to pharmacy education through effective teaching, academic leadership, and curriculum development. His strong blend of pharmaceutical sciences, management, and legal knowledge enables him to guide students with both academic and professional insight. Dr. Bansal is known for his commitment to excellence in teaching and institutional administration. His experience and vision continue to play a vital role in shaping future pharmacy professionals.
Dr. Ashutosh Sharma is an accomplished academician working as Associate Professor in the Department of Pharmaceutics at Jaipur College of Pharmacy, Jaipur. He holds B. Pharm., M. Pharm. (Pharmaceutics), and a Ph.D. in Pharmaceutical Sciences, reflecting strong academic and research credentials. With nine years of teaching experience, he has gained substantial expertise in pharmaceutics and pharmaceutical formulation sciences. He is actively involved in teaching, mentoring, and guiding undergraduate and postgraduate pharmacy students. Dr. Sharma is known for his clear teaching methodology and student-focused approach to learning. His academic contributions play an important role in strengthening quality education in the field of pharmaceutics..
Dr. Yogesh Kumar Garg is a dedicated academician currently working as Professor in the Department of Pharmaceutics at Jaipur College of Pharmacy, Jaipur. He has completed B. Pharm., M. Pharm. (Pharmaceutics), and Ph.D. in Pharmaceutical Sciences, reflecting a strong academic and research foundation. With 11 years of teaching experience, he has gained extensive expertise in pharmaceutics and pharmaceutical sciences. He is actively involved in teaching, mentoring, and guiding pharmacy students at undergraduate and postgraduate levels. Dr. Garg is known for his structured teaching methodology and academic commitment. His contributions play an important role in enhancing the quality of pharmaceutical education..
Ms. Parul Vaishnav is an academic professional working as an Assistant Professor in the Department of Pharmaceutics at Jaipur College of Pharmacy. She has completed her B. Pharm. and M. Pharm. (Pharmaceutics), reflecting a solid foundation in pharmaceutical sciences. With two years of teaching experience, she is actively involved in educating undergraduate pharmacy students. She emphasizes clear understanding of pharmaceutics concepts and practical knowledge. Ms. Vaishnav is recognized for her approachable and student-friendly teaching style. Her contributions support effective learning and academic development within the department.
Mr. Manoj Kumar Gupta is an academician working as an Assistant Professor in the Department of Pharmaceutics at Jaipur College of Pharmacy, Jaipur. He holds B. Pharm., M.S. Pharm. (Pharmacoinformatics), and M. Pharm. (Pharmaceutics), reflecting a strong and multidisciplinary academic background. With four years of teaching experience, he has gained expertise in pharmaceutics and modern pharmacoinformatics approaches. He is actively involved in teaching and mentoring pharmacy students. Mr. Gupta is known for incorporating technology-driven learning methods in pharmaceutical education. His contributions help enhance academic quality and professional development within the department..
Dr. Lokesh Kumar Gautam is a senior academician currently working as Professor in the Department of Pharmaceutics at Jaipur College of Pharmacy, Jaipur. He has completed B. Pharm., M. Pharm., and Ph.D. in Pharmaceutical Sciences, reflecting strong academic and research credentials. With 11 years of teaching experience, he has developed in-depth expertise in pharmaceutics and pharmaceutical sciences. He is actively involved in teaching, mentoring, and guiding undergraduate and postgraduate students. Dr. Gautam is known for his systematic teaching approach and commitment to academic excellence. His contributions play an important role in strengthening pharmaceutical education and research.
