About Book
The Text Book of Pharmaceutical Biotechnology is a comprehensive academic resource designed to provide in-depth knowledge of biotechnological principles as they apply to pharmaceutical sciences. It opens with a foundational introduction to biotechnology, exploring its significance and scope within the pharmaceutical industry. A particular focus is placed on enzyme biotechnology, detailing methods of enzyme immobilization and their wide-ranging applications, along with the crucial role of biosensors. These biosensors, vital in modern pharmaceutical development, are examined in terms of their function and practical utility. The book also introduces the reader to protein engineering and emphasizes the industrial applications of microbial organisms. Detailed sections cover the production of essential enzymes such as amylase, catalase, peroxidase, lipase, protease, and penicillinase, along with general considerations for each.
The second section delves into the core of genetic engineering, providing a solid understanding of cloning vectors, restriction enzymes, and recombinant DNA technology. It emphasizes practical applications of genetic engineering in producing interferons, vaccines like hepatitis B, and critical hormones such as insulin. An introductory look at PCR techniques rounds out this segment. The book proceeds to immunology, presenting concepts of immunity, immunoglobulin structures, MHC functionality, and hypersensitivity responses. It also outlines vaccine production, hybridoma technology, and methods of immune modulation. Further, the text explores advanced immunoblotting techniques such as ELISA, Western blotting, and Southern blotting, explaining their principles, procedures, and relevance in diagnostics. Genetic organization in both eukaryotes and prokaryotes is analyzed, along with microbial genetics mechanisms like transformation, conjugation, and transduction. A separate chapter covers microbial biotransformation and mutations, addressing both theoretical and applied aspects. Fermentation science receives thorough attention, from equipment and sterilization to large-scale production processes for key pharmaceuticals like penicillin and citric acid. Finally, the book examines blood products and plasma substitutes, detailing their collection, processing, and storage, and highlighting their critical role in therapeutic applications. Overall, this textbook serves as an essential guide for students and professionals seeking to master the intersection of biotechnology and pharmaceutical development.
About Author
Dr. Rakesh Singh is an experienced academic professional with over a decade in teaching Currently an Associate Professor at RKDF University, he has been contributing to the Faculty of Pharmacy since 2014. Dr. Singh holds a PhD in Pharmacy from RKDF University, awarded in 2022. Dr. Rakesh Singh published 4 books ,12 research papers ,7 patents ,dedicated to fostering growth, both personally and professionally, in a success-oriented environment
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Dr. Sunil Prakash Chaturvedi is a distinguished academic and researcher, currently serving as Professor and Dean at the School of Pharmacy, Aryavart University, Sehore, MP. An alumnus of Dr. Hari Singh Gaur University, Sagar, he holds an M.Pharm and Ph.D. in Pharmaceutics. With over 25 years of diverse experience in industry, teaching, and research, Dr. Chaturvedi has made significant contributions to pharmaceutical sciences. His expertise lies in fostering innovation, mentoring students, and advancing research in pharmaceutics. Renowned for his leadership, he continues to shape the future of pharmaceutical education and practice.
Mrs. Shalini Singh Negi working as an Assistant Professor in the Department of Biotechnology at SVNIET, Barabanki. I teach Microbiology, Immunology, Bioinformatics and Food Biotechnology. I am dedicated to providing quality education and fostering scientific curiosity among students. My teaching approach emphasizes both conceptual clarity and real-world applications.
Mr. Harendra Prasad is an accomplished Associate Professor in Pharmaceutics with over 15 years of academic experience. He holds an M.Pharm. from Raj Kumar Goel Institute of Technology and a B.Pharm. from Shri Ram Murti Smarak College, both with first division. His research expertise includes solid dispersions, transdermal systems, and solubility enhancement techniques, with multiple publications in reputed pharmaceutical journals. He has guided numerous research projects and actively contributed to national conferences and seminars. Dr. Prasad is a life member of the Indian Pharmaceutical Graduate Association and Pharma Research Library. He is currently serving at Rajeev Gandhi College of Pharmacy, Nautanwa, U.P.
Mr. Diwaker Dadrwal is a dedicated Associate Professor at Sanjivani College of Pharmaceutical Sciences, Khetri (Rajasthan), with 18 years of academic and professional experience. He holds qualifications in D. Pharm, B. Pharm, M. Pharm (Pharmacognosy), and M. Tech (Biotechnology). His expertise lies in natural product research, herbal drug development, and biotechnological applications in pharmacy. Mr. Dadrwal is known for his commitment to quality education and mentoring students in the field of pharmacognosy. He is a life member of APTI and holds an all-India biotech life membership. His contribution to pharmaceutical sciences continues to impact both academia and research.