TEXT BOOK OF PHARMACOLOGY-III

About Book

The Text Book of Pharmacology–III is a comprehensive guide designed to provide advanced knowledge of drugs acting on different systems of the human body and their therapeutic applications. It begins with the study of drugs acting on the respiratory system, including anti-asthmatic agents that relieve bronchospasm, drugs used in the management of COPD to improve airflow, expectorants that enhance mucus clearance, antitussives for cough suppression, nasal decongestants to relieve nasal obstruction, and respiratory stimulants to stimulate breathing. Antiulcer agents are discussed in detail, focusing on drugs that reduce gastric acid secretion or protect the gastric mucosa. The book also includes drugs used for managing constipation and diarrhea, providing insights into both stimulants and inhibitors of bowel movements. Appetite stimulants and suppressants are covered, along with digestants and carminatives that improve digestion and reduce flatulence. Emetics and antiemetics are described to explain agents that induce or prevent vomiting. The chemotherapy section starts with general principles, followed by sulfonamides and cotrimoxazole. A major emphasis is placed on antibiotics, including penicillins, cephalosporins, chloramphenicol, macrolides, quinolones, fluoroquinolones, tetracyclines, and aminoglycosides, describing their mechanisms, uses, and adverse effects. Antitubercular and antileprotic agents are thoroughly explained to highlight treatment strategies for infectious diseases. Further sections cover antifungal agents, antiviral drugs, anthelmintics for parasitic worms, antimalarial drugs, and antiamoebic agents. Chemotherapy for urinary tract infections, sexually transmitted diseases, and malignancy is also addressed. Immunopharmacology is presented in detail, discussing immunostimulants, immunosuppressants, protein drugs, monoclonal antibodies, and targeted therapies. The principles of toxicology are elaborated, covering acute, subacute, and chronic toxicities, genotoxicity, carcinogenicity, teratogenicity, and mutagenicity, along with general management of poisoning. Special poisoning cases, including barbiturates, morphine, organophosphorus compounds, lead, arsenic, and mercury, are also discussed with clinical symptoms and treatment. Finally, chronopharmacology is explained with definitions of rhythms, biological clocks, and their therapeutic significance, introducing the concept of chronotherapy. Overall, the book integrates systemic pharmacology, chemotherapy, immunopharmacology, toxicology, and chronopharmacology in a structured manner, serving as a valuable resource for pharmacy and medical students aiming to master drug actions and clinical applications.