About Book
The Textbook of Pharmacology-II provides a comprehensive understanding of various drugs that act on vital physiological systems of the human body. It begins with an in-depth exploration of the cardiovascular system, introducing the electrophysiology of the heart to help readers grasp how drugs influence cardiac rhythm and function. The section on congestive heart failure elaborates on the therapeutic strategies and pharmacological agents used to restore cardiac efficiency. Further, antihypertensive drugs are discussed in detail, focusing on their mechanisms, classifications, and clinical uses. The subsequent unit extends the discussion to anti-anginal, anti-arrhythmic, and anti-hyperlipidemic drugs, offering insights into the pharmacological management of coronary artery diseases and lipid disorders. Topics such as drugs used in shock therapy and hematinics emphasize their role in maintaining circulatory stability and correcting anemic conditions. The third section continues with agents affecting blood coagulation, including coagulants, anticoagulants, fibrinolytics, and antiplatelet drugs, followed by plasma volume expanders used in emergency medicine. The urinary system pharmacology chapter covers diuretics and antidiuretics, highlighting their role in fluid balance and renal function. Moving to autacoids, the book details the pharmacology of histamine, serotonin (5-HT), prostaglandins, thromboxanes, leukotrienes, angiotensin, bradykinin, and substance P, describing their physiological and pathological significance. The next section covers NSAIDs, anti-gout, and antirheumatic drugs, vital in the management of inflammation and joint disorders. The endocrine pharmacology chapters present the mechanisms and clinical uses of pituitary, thyroid, parathyroid, pancreatic, and adrenal hormones, as well as oral hypoglycemics and glucagon. A continuation explores sex hormones— androgens, estrogens, and progesterone— along with oral contraceptives and uterine drugs. Finally, the bioassay section introduces its principles, applications, and types, explaining experimental methods for determining drug potency. Specific bioassays for insulin, oxytocin, vasopressin, ACTH, d-tubocurarine, digitalis, histamine, and serotonin are discussed, emphasizing the importance of biological testing in pharmacological research and standardization.
About Author
Mrs Anamika Kulshrestha is currently working as Associate professor at IIMT College of Pharmacy, Greater Noida. She has completed her M.Pharm from Shri Ram College of Pharmacy, Banmore, Morena, Madhya Pradesh in 2012. She is pursuing PhD from Maharishi University OF Information And Technology, MUIT, Lucknow, Uttar Pradesh. She has 12.8 years of academics and teaching experience in pharmaceutical field. She has published research and review article in national and international journals. She received four Indian patent grants. She has keen interest in research in Pharmacology, Pharmacovigilance, Clinical trials etc. She has participated in various webinar, seminar, national and international conference and FDP. She has given video lectures on many subjects. She has life time membership of APP and nominated as Best Teacher award in International Conference.
Dr. Mahesh Kumar Posa currently working as Professor in Department of Pharmacology, School of Pharmaceutical Sciences, Jaipur National University, Jaipur-302017, Rajasthan, India. He completed his B. Pharm from Kakatiya University, Warangal, India and M. Pharm and Ph.D. from Birla Institute of Technology-Mesra-Ranchi, India. He had 18 Years of rich teaching and research experience. He worked in various reputed universities such as GITAM University - Visakhapatnam Campus, SVKM’S NMIMS University - Hyderabad Campus. He worked as PDF Trainee – Team Member in Pharmaceutical Industry (Dr. Reddy’s Laboratories) and had expertise in the manufacturing Soft gelatin capsules and Topical formulations. His area of research is Neuropharmacology, Metabolic disorders, Dermatological disorders and Drug delivery. He published 30 research and review articles in various International and National journals and credited with 12 patents.
Prof. (Dr.) Bhupendra Chauhan is the Director of the Adarsh Vijendra Institute of Pharmaceutical Sciences, Shobhit University, Gangoh. With more than 15 years of academic and research experience, he is recognized as a committed scholar and academic leader. He earned his Ph.D. in 2019 under the supervision of Prof. (Dr.) Ranjit Singh at Shobhit University, Gangoh. He completed his M.Pharm. in Pharmacology at the School of Pharmaceutical Sciences, Shobhit University, Meerut in 2010, following his B.Pharm. at Kurukshetra University, Haryana. Dr. Chauhan has published over 50 research and review papers in peer-reviewed journals, filed 10 patents, and guided 6 Master’s and 4 Ph.D. scholars. He is presently supervising 8 Ph.D. scholars, underscoring his commitment to research mentorship. He is a life member of the Association of Pharmaceutical Teachers of India (APTI) and the Society of Pharmaceutical Education and Research (SPER). Through his work in teaching, research, and professional service, Dr. Chauhan continues to make significant contributions to the advancement of Pharmaceutical Sciences.
Dr. Pritam Rajkumar Siraskar is currently serving as Senior Manager and Head of Production at Glenmark Pharmaceuticals, Indore, India. He holds a Master of Pharmacy degree from RGPV, Bhopal, and a Ph.D. in Pharmaceutical Sciences, with over 15 years of extensive experience in OSD, liquid, semisolid, dry syrup, and suppository manufacturing, quality management, technology transfer, research and development, and execution of greenfield and brownfield projects. Dr. Siraskar has authored several research publications and book chapters in reputed journals and academic volumes. He is also actively guiding six Ph.D. research scholars in the field of pharmaceutical sciences. He is a certified Six Sigma Black Belt and Green Belt professional with PMP and PMI certifications, and has collaborated with leading pharmaceutical organizations including Ranbaxy, Intas, Mylan, Wockhardt, Hetero, Cipla, and Glenmark. Passionate about lifelong learning, he has successfully completed over 1000 professional certifications across technical, regulatory, and managerial domains.
Dr. Rekha Tarasingh Rajput, currently working as Associate Professor,Sharda School of Pharmacy, Sharda University, Agra, (Formerly Anand College of Pharmacy, Keetham, Agra.), Agra-282005, Uttar Pradesh, India. She has completed her graduation from L.M. College of Pharmacy, Ahmedabad (Gujarat University) and post-graduation from K.L.E. Society's College of Pharmacy, Belgaum (Rajiv Gandhi University of Health Sciences) one of the prestigious and well-known universities and completed her Ph. D in Pharmaceutical Sciences on the topic entitled “Evaluation and Development of Anti-diabetic Polyherbal Formulation of Indian Medicinal Plants”. She has a total of 18+ years of teaching experience. She has more than 33 publications, 17 patents, 07 books and 01 book chapter and more than 100 International and national conferences attended. She is interested in the extraction, isolation, and purification of different compounds from medicinal plants and the development of herbal formulations.