TEXT BOOK OF PHARMACOLOGY-II

About Book

The Text Book of Pharmacology-II is a comprehensive academic resource designed for pharmacy and medical students to gain an in-depth understanding of the pharmacological principles and therapeutic applications of important classes of drugs. The book begins with an extensive exploration of the cardiovascular system, covering its electrophysiology and the pharmacology of drugs used in the management of congestive heart failure, hypertension, angina pectoris, arrhythmias, hyperlipidemia, shock, and hematinic therapy. It progresses into advanced topics in cardiovascular pharmacology, including coagulants, anticoagulants, fibrinolytics, antiplatelet agents, and plasma volume expanders, offering clear mechanisms of action, clinical uses, and adverse effects. The section on the urinary system focuses on diuretics and antidiuretics, explaining their roles in managing fluid balance disorders. A dedicated portion of the book is devoted to autacoids and related drugs, elaborating on mediators like histamine, serotonin, prostaglandins, thromboxanes, leukotrienes, angiotensin, bradykinin, and substance P, along with their antagonists. The second part of the autacoid section details the pharmacology of NSAIDs, anti-gout agents, and antirheumatic drugs. The endocrine pharmacology chapters provide an integrated view of hormone physiology and pharmacology, discussing anterior pituitary hormones, thyroid hormones, calcium-regulating hormones, insulin, oral hypoglycemics, ACTH, and corticosteroids. The subsequent section on endocrine pharmacology covers androgens, anabolic steroids, estrogens, progesterone, oral contraceptives, and drugs acting on the uterus. The book concludes with an important chapter on bioassay, explaining its principles, applications, and various methods, with specific examples such as bioassay of insulin, oxytocin, vasopressin, ACTH, d-tubocurarine, digitalis, histamine, and serotonin. Throughout, the text combines basic principles, mechanisms of action, clinical indications, side effects, and recent therapeutic advances in a logical and easy-to-follow format. Rich with academic depth, the book is an essential guide for mastering pharmacology, bridging theoretical concepts with clinical application, and preparing students for professional examinations and practice.